SMIP34
Product Specifications
CAS Number
1189710-20-0
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
SMIP34 is an inhibitor of PELP1, binding to this target with a dissociation constant (Kd) of 37.4 μM. It demonstrates efficacy in inhibiting the proliferation of cancer cells and tumor progression. Specifically, SMIP34 is effective in breast cancer research, showing activity against wild-type (WT), mutant (MT) estrogen receptor-positive (ER+), and treatment-resistant (TR) -ER+ breast cancers.
Smiles
O=C(NC1=CC=C(C(Cl)=C1)C)C2=NN3C(=C2)C(=O)N(CCCC)C(C(=O)NC4CCCC4)(C)C3
Molecular Formula
C25H32ClN5O3
Molecular Weight
486.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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