HDAC9-IN-1
Product Specifications
Target
HDAC
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
HDAC9-IN-1 (Compound 7g) is a potent inhibitor of HDAC9, exhibiting an IC50 of 40 nM. This compound effectively suppresses various human cancer cell lines, induces apoptosis, modulates caspase-related proteins and p38, and results in DNA damage.
Smiles
C([C@@H](NC(CN1CCC(NC2=CC=C(C=C2)C=3C=C(N=NC3)C4=C(O)C=CC=C4)CC1)=O)[C@@](C)(C)C)(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C7=C(C)N=CS7)=O)C[C@@H](O)C5
Molecular Formula
C27H22N4O3S
Molecular Weight
482.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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