Multi-kinase inhibitor 4
Product Specifications
CAS Number
2648279-77-8
Target
FLT, PDGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Multi-kinase inhibitor 4 (compound 14) serves as an orally effective inhibitor targeting FLT1, KDR, FLT3, FLT4, PDGFRα, and PDGFRβ, exhibiting IC50 values of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, and 0.89 nM respectively. This compound plays a crucial role in cancer research.
Smiles
O=C(NC=1ON=C(C1)C(C)(C)C)CC2=CC=C(C=C2)N3C=NC=4C=C(C=CC43)C=5C=NNC5
Molecular Formula
C25H24N6O2
Molecular Weight
440.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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