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Multi-kinase inhibitor 4

Product Specifications

CAS Number

2648279-77-8

Target

FLT|||PDGFR

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis

Bioactivity

Multi-kinase inhibitor 4 (compound 14) serves as an orally effective inhibitor targeting FLT1, KDR, FLT3, FLT4, PDGFR?, and PDGFR?, exhibiting IC50 values of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, and 0.89 nM respectively. This compound plays a crucial role in cancer research.

Smiles

O=C(NC=1ON=C(C1)C(C)(C)C)CC2=CC=C(C=C2)N3C=NC=4C=C(C=CC43)C=5C=NNC5

Molecular Formula

C25H24N6O2

Molecular Weight

440.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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