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Dyrk1A-IN-11

Product Specifications

CAS Number

3058626-26-6

Target

DYRK

Related Pathways

Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors

Bioactivity

Dyrk1A-IN-11 (compound 166) is an effective inhibitor targeting dual-specificity tyrosine phosphorylation-regulated 1A (DYRK1A) with an EC50 of 0.0021 μM. Additionally, this compound inhibits the phosphorylation of Tau (Thr212) with an EC50 of 0.0361 μM.

Smiles

FC=1C(=C2N(C1)N=C(N[C@H]3C(F)(F)CN(CC3)C4COC4)N=C2)C=5N=C6C(=CC5)N=C(C)N6CC(F)F

Molecular Formula

C23H23F5N8O

Molecular Weight

522.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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