Dyrk1A-IN-11
Product Specifications
CAS Number
3058626-26-6
Target
DYRK
Related Pathways
Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors
Bioactivity
Dyrk1A-IN-11 (compound 166) is an effective inhibitor targeting dual-specificity tyrosine phosphorylation-regulated 1A (DYRK1A) with an EC50 of 0.0021 µM. Additionally, this compound inhibits the phosphorylation of Tau (Thr212) with an EC50 of 0.0361 µM.
Smiles
FC=1C(=C2N(C1)N=C(N[C@H]3C(F)(F)CN(CC3)C4COC4)N=C2)C=5N=C6C(=CC5)N=C(C)N6CC(F)F
Molecular Formula
C23H23F5N8O
Molecular Weight
522.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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