[Au (L4) (CyJohnPhos) ]SbF6
Product Specifications
Target
COX, Apoptosis, Reactive Oxygen Species
Related Pathways
Neuroscience, Immunology/Inflammation, Apoptosis, NF-κB, Metabolism
Bioactivity
[Au (L4) (CyJohnPhos) ]SbF6 is a gold-containing compound that exhibits inhibitory effects on cyclooxygenase-1/2 (COX-1/2), suppresses the proliferation of colon cancer cells Caco2-/TC7 with an IC50 of 0.98 μM, and induces cell apoptosis (apoptosis) . Additionally, [Au (L4) (CyJohnPhos) ]SbF6 acts as an inhibitor of thioredoxin reductase (TrxR) and demonstrates antioxidative activity by modulating ROS levels.
Molecular Formula
C44H56AuF6NO4PSSb
Molecular Weight
1158.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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