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[Au (L4) (CyJohnPhos) ]SbF6

Product Specifications

Target

COX, Apoptosis, Reactive Oxygen Species

Related Pathways

Neuroscience, Immunology/Inflammation, Apoptosis, NF-κB, Metabolism

Bioactivity

[Au (L4) (CyJohnPhos) ]SbF6 is a gold-containing compound that exhibits inhibitory effects on cyclooxygenase-1/2 (COX-1/2), suppresses the proliferation of colon cancer cells Caco2-/TC7 with an IC50 of 0.98 μM, and induces cell apoptosis (apoptosis) . Additionally, [Au (L4) (CyJohnPhos) ]SbF6 acts as an inhibitor of thioredoxin reductase (TrxR) and demonstrates antioxidative activity by modulating ROS levels.

Molecular Formula

C44H56AuF6NO4PSSb

Molecular Weight

1158.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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