PROTAC SMARCA2 degrader-22
Product Specifications
CAS Number
2760246-90-8
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTAC SMARCA2 degrader-22 (Compound 5) is a PROTAC degrader designed to degrade SMARCA2, achieving a degradation efficacy of 94% at 100 nM. This compound also inhibits the proliferation of A549 cells with an EC50 of less than 250 nM.
Smiles
C([C@@H](NC(CN1CCN(CC1)C2=CC=C(C=N2)C=3C=C(N=NC3)C4=C(O)C=CC=C4)=O)[C@](C)(C)C)(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C=7SC=NC7C)=O)C[C@@H](O)C5
Molecular Formula
C44H51N9O5S
Molecular Weight
818
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![CD40L (CD40LG) Rabbit Monoclonal Antibody [Clone ID: YMF323.6]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP3-28269JF525 0.1 mL
Human Monoclonal IDO2 Antibody (LIMR patent anti-IDO2) [Janelia Fluor 525]
Ask
View Details 