PROTAC SMARCA2 degrader-22
Product Specifications
CAS Number
2760246-90-8
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTAC SMARCA2 degrader-22 (Compound 5) is a PROTAC degrader designed to degrade SMARCA2, achieving a degradation efficacy of 94% at 100 nM. This compound also inhibits the proliferation of A549 cells with an EC50 of less than 250 nM.
Smiles
C([C@@H](NC(CN1CCN(CC1)C2=CC=C(C=N2)C=3C=C(N=NC3)C4=C(O)C=CC=C4)=O)[C@](C)(C)C)(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C=7SC=NC7C)=O)C[C@@H](O)C5
Molecular Formula
C44H51N9O5S
Molecular Weight
818
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7265893-01 48 Well
Sheep Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase ELISA Kit
Ask
View Details MBS7265893-02 96 Well
Sheep Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase ELISA Kit
Ask
View Details MBS7265893-03 5x 96 Well
Sheep Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase ELISA Kit
Ask
View Details 
MBS7265893-04 10x 96 Well
Sheep Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase ELISA Kit
Ask
View Details