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SJ6145

Product Specifications

CAS Number

1010913-79-7

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

SJ6145 is an effective ligand for KLHDC2SBD, exhibiting a dissociation constant (Kd) of 16.9 μM as determined by Surface Plasmon Resonance (SPR) testing. It has shown an inhibitory concentration 50% (IC50) value of 42 μM in assays testing the inhibition of the binding between KLHDC2SBD and a diglycol degradation peptide.

Smiles

O=C(O)CNC(=O)CC=1N=C(SC1)C=2C=CC=CC2F

Molecular Formula

C13H11FN2O3S

Molecular Weight

294.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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