Keap1-Nrf2-IN-23
Product Specifications
CAS Number
2771115-65-0
Target
Nrf2
Related Pathways
Immunology/Inflammation
Bioactivity
Keap1-Nrf2-IN-23 (compound 56) acts as an inhibitor of the Keap1–Nrf2 PPI (IC50=16.0 nM) . It exhibits a Kd value of 3.07 nM when binding to Keap1 and demonstrates oral activity.
Smiles
O=C(O)CC(C1=CC=2N=NN(C2C(OC)=C1)C)C=3C=CC=C4C3CCN(C(=O)C5=CC=C(OC(C)C)C=C5Cl)C4
Molecular Formula
C30H31ClN4O5
Molecular Weight
563.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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