Keap1-Nrf2-IN-23

Product Specifications

CAS Number

2771115-65-0

Target

Nrf2

Related Pathways

Immunology/Inflammation

Bioactivity

Keap1-Nrf2-IN-23 (compound 56) acts as an inhibitor of the Keap1–Nrf2 PPI (IC50=16.0 nM) . It exhibits a Kd value of 3.07 nM when binding to Keap1 and demonstrates oral activity.

Smiles

O=C(O)CC(C1=CC=2N=NN(C2C(OC)=C1)C)C=3C=CC=C4C3CCN(C(=O)C5=CC=C(OC(C)C)C=C5Cl)C4

Molecular Formula

C30H31ClN4O5

Molecular Weight

563.04

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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