UNC0638 hydrate
Product Specifications
CAS Number
1255517-77-1
Target
Histone Methyltransferase|||Influenza Virus|||Autophagy
Related Pathways
Microbiology/Virology|||Chromatin/Epigenetic|||Autophagy
Bioactivity
UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.
Smiles
O.N=1C=2C=C(OCCCN3CCCC3)C(OC)=CC2C(=NC1C4CCCCC4)NC5CCN(CC5)C(C)C
Molecular Formula
C30H49N5O3
Molecular Weight
527.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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