Bfl-1-IN-5
Product Specifications
Target
Bcl-2 Family, Caspase
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
Bfl-1-IN-5 (Compound (R, R, S) -26) is a selective inhibitor of Bfl-1, demonstrating an IC50 of 0.022 μM. This compound enhances the activity of caspase-3/7, with an EC50 of 0.37 μM, and also inhibits the viability of SU-DHL-1 cells, showing an EC50 of 1.3 μM.
Smiles
C(CNC(C)=O)[C@H]1C=2C3=C(C=CC2CC1)N=C(C)O3
Molecular Formula
C24H24F3N3O2
Molecular Weight
443.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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