AK-1690
Product Specifications
CAS Number
2984505-88-4
Target
PROTACs, STAT
Related Pathways
JAK/STAT signaling, PROTAC, Stem Cells
Purity
>99.99%
Bioactivity
AK-1690 is a potent and selective STAT6 PROTAC degrader that induces degradation of STAT6 proteins in cells (DC50=1 nM) and depletes STAT6 proteins in mouse tissues, which can be used in cancer research.
Smiles
C(#CCCCCCO[C@H]1C[C@@H](C(=O)N2C[C@H](OCC2)C3=CC=CC=C3)N(C([C@@H](NC(=O)C4=CC=5C(S4)=CC=C(C(P(=O)(O)O)(F)F)C5)[C@@](C)(C)C)=O)C1)C6=C7C(C(=O)N(C7)C8C(=O)NC(=O)CC8)=CC=C6
Molecular Formula
C51H56F2N5O11PS
Molecular Weight
1016.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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