Metallo-β-lactamase-IN-16
Product Specifications
CAS Number
2058069-25-1
Target
Antibacterial, Beta-lactamase
Related Pathways
Microbiology/Virology
Bioactivity
Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.
Smiles
O=S(=O)(N)C1=C(C2=NN=NN2)C(=CC=C1S(=O)(=O)CCN)C=3C=CC=C4SC(=NC43)N
Molecular Formula
C16H16N8O4S3
Molecular Weight
480.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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