Metallo-?-lactamase-IN-16
Product Specifications
CAS Number
2058069-25-1
Target
Antibacterial|||Beta-lactamase
Related Pathways
Microbiology/Virology
Bioactivity
Metallo-?-lactamase-IN-16 (compound 18), a sulfone-containing metallo-?-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-?-lactamases, including NDM-1 (New Delhi metallo-?-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-?-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.
Smiles
O=S(=O)(N)C1=C(C2=NN=NN2)C(=CC=C1S(=O)(=O)CCN)C=3C=CC=C4SC(=NC43)N
Molecular Formula
C16H16N8O4S3
Molecular Weight
480.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
RR204497L3V 200 µL
Cd83 (NM_001108410) Rat Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 