Metallo-?-lactamase-IN-16
Product Specifications
CAS Number
2058069-25-1
Target
Antibacterial|||Beta-lactamase
Related Pathways
Microbiology/Virology
Bioactivity
Metallo-?-lactamase-IN-16 (compound 18), a sulfone-containing metallo-?-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-?-lactamases, including NDM-1 (New Delhi metallo-?-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-?-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.
Smiles
O=S(=O)(N)C1=C(C2=NN=NN2)C(=CC=C1S(=O)(=O)CCN)C=3C=CC=C4SC(=NC43)N
Molecular Formula
C16H16N8O4S3
Molecular Weight
480.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6443270-01 0.1 mL
VPS4B (Vacuolar Protein Sorting 4B, MIG1, SKD1, SKD1B, VPS4-2) (PE)
Sign In for Pricing
View Details 
MBS6443270-02 5x 0.1 mL
VPS4B (Vacuolar Protein Sorting 4B, MIG1, SKD1, SKD1B, VPS4-2) (PE)
Sign In for Pricing
View Details 
MBS651086-01 0.02 mg
Tumor Necrosis Factor alpha, Recombinant, Canine (TNFa)
Sign In for Pricing
View Details MBS651086-02 5x 0.02 mg
Tumor Necrosis Factor alpha, Recombinant, Canine (TNFa)
Sign In for Pricing
View Details 040912-HRP 200 µL
RBP7, ID (RBP7, Retinoid-binding protein 7, Cellular retinoic acid-binding protein 4, Cellular retinoic acid-binding protein IV) (Azide free) (HRP) discontinued
Sign In for Pricing
View Details