PROTAC MPS1 degrader 2

Product Specifications

Target

Aurora Kinase, Kinesin, PROTACs

Related Pathways

Chromatin/Epigenetic, PROTAC, Cell Cycle/Checkpoint, Cytoskeletal Signaling

Bioactivity

PROTAC MPS1 Degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB with DC50 values of 42.0, 2.1, and 154.0 nM respectively. It is utilized in the research of acute myeloid leukemia.

Smiles

O=C(OC1=CC=C(C=C1)CCC(=O)ON2C(=O)CCC2=O)C3=C4C=CC=CC4=[N+](C=5C=CC=CC53)C.O=S(=O)([O-])C(F)(F)F

Molecular Formula

C41H41N11O8S

Molecular Weight

847.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

PC1007279-01 50 mg

3-Bromo-5-fluoro-4-methylbenzo[b]thiophene

View Details

PC1007279-02 100 mg

3-Bromo-5-fluoro-4-methylbenzo[b]thiophene

View Details

PC1007279-03 250 mg

3-Bromo-5-fluoro-4-methylbenzo[b]thiophene

View Details

PC1007279-04 1 g

3-Bromo-5-fluoro-4-methylbenzo[b]thiophene

View Details

044182-APC 200 µL

ZNF302, NT (ZNF302, ZNF135L, ZNF140L, ZNF327, Zinc finger protein 302, Zinc finger protein 135-like, Zinc finger protein 140-like, Zinc finger protein 327) (APC) discontinued

View Details

GTR10351439 96 Well

Rat Carcinoembryonic antigen related cell adhesion molecule 7 (CEACAM7) ELISA Kit

View Details