PROTAC MPS1 degrader 2
Product Specifications
Target
Aurora Kinase, Kinesin, PROTACs
Related Pathways
Chromatin/Epigenetic, PROTAC, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Bioactivity
PROTAC MPS1 Degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB with DC50 values of 42.0, 2.1, and 154.0 nM respectively. It is utilized in the research of acute myeloid leukemia.
Smiles
O=C(OC1=CC=C(C=C1)CCC(=O)ON2C(=O)CCC2=O)C3=C4C=CC=CC4=[N+](C=5C=CC=CC53)C.O=S(=O)([O-])C(F)(F)F
Molecular Formula
C41H41N11O8S
Molecular Weight
847.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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