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PROTAC MPS1 degrader 2

Product Specifications

Target

Aurora Kinase|||Kinesin|||PROTACs

Related Pathways

Chromatin/Epigenetic|||PROTAC|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling

Bioactivity

PROTAC MPS1 Degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB with DC50 values of 42.0, 2.1, and 154.0 nM respectively. It is utilized in the research of acute myeloid leukemia.

Smiles

O=C(OC1=CC=C(C=C1)CCC(=O)ON2C(=O)CCC2=O)C3=C4C=CC=CC4=[N+](C=5C=CC=CC53)C.O=S(=O)([O-])C(F)(F)F

Molecular Formula

C41H41N11O8S

Molecular Weight

847.9

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/264724928207519767/T201010

Available Sizes

Curated Selection

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