Immunoproteasome activator 1
Product Specifications
CAS Number
901728-48-1
Target
Proteasome
Related Pathways
Proteases/Proteasome, Ubiquitination
Bioactivity
Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.
Smiles
O=C(NC1=CC=CC(=C1)C(=O)C)C2=CC=3C=C4C5=C(C3OC2=N)CCCN5CCC4
Molecular Formula
C24H23N3O3
Molecular Weight
401.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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