DH-18
Product Specifications
Target
MMP, Apoptosis
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
DH-18 is an inhibitor of matrix metalloproteinase-2 (MMP-2), exhibiting IC50 values of 139.45 nM for MMP-2, 518.11 nM for MMP-9, and 833.34 nM for MMP-8. The compound promotes cell apoptosis and causes cell cycle arrest in the G0/G1 phase. DH-18 also inhibits cell growth, making it potential for research in chronic myeloid leukemia.
Molecular Formula
C26H23F6N3O5S
Molecular Weight
603.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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