What is the catalog number for PRMT5-IN-45?

The catalog number for PRMT5-IN-45 is T200980.

What sizes are available for PRMT5-IN-45?

PRMT5-IN-45 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PRMT5-IN-45 come in?

PRMT5-IN-45 is available in 2 different pack sizes.

Is PRMT5-IN-45 in stock?

PRMT5-IN-45 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PRMT5-IN-45?

PRMT5-IN-45 is manufactured by Molfinity.

What is the estimated delivery time for PRMT5-IN-45?

Estimated delivery time for PRMT5-IN-45 is approximately 10 business day(s), depending on your location.

PRMT5-IN-45

Product Specifications

Target

Apoptosis, Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic, Apoptosis

Bioactivity

PRMT5-IN-45 (compound 36) is a potent and selective inhibitor of PRMT5, exhibiting an IC50 value of 3 nM. This compound effectively reduces the levels of symmetrical dimethylarginine (sDMA) and inhibits the proliferation of the MOLM-13 cell line by inducing apoptosis and causing cell cycle arrest.