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A?-IN-10

Product Specifications

Target

Beta Amyloid

Related Pathways

Neuroscience

Bioactivity

A?-IN-10 (Compound Alz-5) is a bifunctional copper chelator and an inhibitor of beta-amyloid (A?), interacting with A? aggregates to reduce their neurotoxicity. This compound also displays antioxidative properties and exhibits moderate cytotoxicity in SH-SY5Y and HepG2 cells in the presence of CuCl2, with IC50 values of 65.5 and 31.2 ?M, respectively. Additionally, A?-IN-10 reduces the increase in cell rigidity caused by A?.

Molecular Formula

C30H35N7S2

Molecular Weight

557.78

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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