JMS-175-2
Product Specifications
CAS Number
3042887-70-4
Target
DUB
Related Pathways
DNA Damage/DNA Repair, Ubiquitination, Cell Cycle/Checkpoint
Bioactivity
JMS-175-2 is an effective inhibitor of the BRCC36 isopeptidase complex (BRISC), exhibiting an IC50 of 3.8 μM. This compound plays a crucial role in diseases mediated by Type I interferon.
Smiles
O=C(NC1CCNCC1)C2=NN(C=C2NC(=O)C=3C(Cl)=CC=CC3Cl)C(=O)C=4C(Cl)=CC=CC4Cl
Molecular Formula
C23H19Cl4N5O3
Molecular Weight
555.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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