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C-Kit-IN-8

Product Specifications

CAS Number

2941024-89-9

Target

C-Kit

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC50 greater than 1 μM. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC50 greater than 0.1 μM.

Smiles

O=C(NC1=CC=C(C=C1)NC=2N=CN=C3C=C(OCCOC)C=C(F)C32)CCN4C(=O)CCC4

Molecular Formula

C24H26FN5O4

Molecular Weight

467.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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