ZG-2305
Product Specifications
CAS Number
2962103-54-2
Target
HIF
Related Pathways
Chromatin/Epigenetic, Angiogenesis
Bioactivity
ZG-2305 is a selective, orally active inhibitor of FIH with Ki values of 79.6 nM and 2786 nM for FIH and PHD2, respectively. It increases EGLN3 gene expression, reduces cellular triglyceride levels, and decreases lipid accumulation, making it suitable for obesity and fatty liver disease research.
Smiles
O=C(O)CNC(=O)C=1N=CC(=CC1O)C=2ON=C(C2)C=3C=C(Cl)C=C(Cl)C3
Molecular Formula
C17H11Cl2N3O5
Molecular Weight
408.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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