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ZG-2305

Product Specifications

CAS Number

2962103-54-2

Target

HIF

Related Pathways

Chromatin/Epigenetic|||Angiogenesis

Bioactivity

ZG-2305 is a selective, orally active inhibitor of FIH with Ki values of 79.6 nM and 2786 nM for FIH and PHD2, respectively. It increases EGLN3 gene expression, reduces cellular triglyceride levels, and decreases lipid accumulation, making it suitable for obesity and fatty liver disease research.

Smiles

O=C(O)CNC(=O)C=1N=CC(=CC1O)C=2ON=C(C2)C=3C=C(Cl)C=C(Cl)C3

Molecular Formula

C17H11Cl2N3O5

Molecular Weight

408.19

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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