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PROTAC BRM/BRG1 degrader-4

Product Specifications

Target

PROTACs, Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic, PROTAC

Bioactivity

PROTAC BRM/BRG1 degrader-4 (example 047) is a potent degrader targeting both BRM and BRG1, demonstrating DC50 values of 0.21 nM and 3.4 nM respectively in SW1573 cells.

Smiles

N#CC=1C=C2N=C(NC2=C(OC)C1)C3=C(N=CC(C4=CC(F)=CC(=C4)C)=C3N5CCC(N)CC5)N

Molecular Formula

C44H52N10O6S

Molecular Weight

849.01

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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