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WZ-2-033

Product Specifications

CAS Number

2416196-47-7

Target

STAT

Related Pathways

JAK/STAT signaling, Stem Cells

Bioactivity

WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 μM respectively.

Smiles

O=C(NC=1C=CC=2C=CS(=O)(=O)C2C1)CC3=C(N=C4C=C(OC)C=CN43)C5=CC=C(C=C5)C(F)(F)F

Molecular Formula

C25H18F3N3O4S

Molecular Weight

513.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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