WEE1-IN-11
Product Specifications
CAS Number
2975172-98-4
Target
Wee1
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
WEE1-IN-11 (Compound 13) serves as a potent CDK2 inhibitor with an IC50 of 2.0 nM. It exhibits inhibitory effects on several cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr, with respective IC50 values of 93.9, 34.5, 86.7, 23.1, and 85 nM.
Smiles
N(C=1N=C(C(=CN1)C2=CN=CS2)C=3SC(=NC3)N4CC[C@H](F)C4)C5=CC(OC)=C(C=C5)N6CCN(C)CC6
Molecular Formula
C26H29FN8OS2
Molecular Weight
552.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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