NLRP3-IN-56
Product Specifications
CAS Number
3048421-42-4
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-56 (compound 062) is an inhibitor of NLRP3. It effectively suppresses the secretion of IL-1β in THP-1 cells, demonstrating an IC50 of 9.7 nM. NLRP3-IN-56 is useful for research into NLRP3-mediated symptoms and/or diseases.
Smiles
N(C[C@@H](CO)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CC(C#CC)=C2
Molecular Formula
C20H18ClN3O3
Molecular Weight
383.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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