Menin-MLL inhibitor 34
Product Specifications
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
Menin-MLL inhibitor 34 (Compound 37) is a selective and potent inhibitor of Menin-MLL, exhibiting an IC50 of 18.21 nM against Menin. This compound effectively reduces Menin protein levels and downregulates MEN1 transcription, demonstrating sustained anti-leukemia effects.
Smiles
O=C1C2=C(C=C(N=C2N(C(=O)N1C)C)N3CCN(C)CC3)NCC(=O)NC=4C=CC=C(Cl)C4
Molecular Formula
C40H54FN9O4S
Molecular Weight
775.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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