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PROTAC SMARCA2/4-degrader-34

Product Specifications

Target

Epigenetic Reader Domain|||PROTACs

Related Pathways

Chromatin/Epigenetic|||PROTAC

Bioactivity

PROTAC SMARCA2/4-degrader-34 (compound 38) serves as an effective degrader of both SMARCA2 and SMARCA4. It demonstrates binding affinity to PXR with a DC50 value of 85.1 nM and reduces the protein expression of 3xFLAG-PXR.

Smiles

O([C@H](CCNC)C1=CC=CS1)C=2C3=C(C=CC2)C=CC=C3

Molecular Formula

C58H78N8O13S

Molecular Weight

1127.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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