SW063058
Product Specifications
CAS Number
533876-30-1
Target
Autophagy|||Others
Related Pathways
Autophagy|||Others
Bioactivity
SW063058 is an autophagy inducer that specifically disrupts the interaction between Beclin 1 and Bcl-2 without affecting the interactions of Bcl-2 with pro-apoptotic members (such as Bax and BIM) . By inhibiting the negative regulation of Beclin 1 (key to autophagy initiation) by Bcl-2, SW063058 enhances autophagic activity without inducing cytotoxicity, apoptosis, or other forms of cell death in vitro.
Smiles
O=C1NC2=CC=C(Br)C=C2C(C3=CC=C(F)C=C3)N(C(=O)C=4C=CC=CC4I)C1
Molecular Formula
C22H15BrFIN2O2
Molecular Weight
565.17
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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