ST2-IN-1
Product Specifications
Target
Interleukin
Related Pathways
Immunology/Inflammation
Bioactivity
ST2-IN-1 (compound 31) is an inhibitor of Stimulation-2 (ST2) with an IC50 of 7 μM in AlphaLISA assays and 7.19 μM in HEK-Blue assays. This compound effectively attenuates the ST2/IL-33 signaling pathway in human hypertrophic cells.
Smiles
N(CC1=CC=C(/C=C/C(O)=O)C=C1)(CC)C2=C(C=CC(C(F)(F)F)=C2)N3CC=4C(CC3)=CC(O)=CC4
Molecular Formula
C27H33N5O2
Molecular Weight
459.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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