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STING-IN-10

Product Specifications

Target

PROTACs, STING

Related Pathways

PROTAC, Immunology/Inflammation

Bioactivity

STING-IN-10 (P8) serves as both a dual degrader and inhibitor of STING, exhibiting an impressive DC50 value of 2.58 μM in THP-1 cells. This compound also demonstrates anti-inflammatory activity.

Smiles

O=C(N)C(N(C1=NC(N)=C(S1)C(=O)C2=CC=C(C=C2)S(F)(F)(F)(F)F)C3=CC=C(F)C=C3)C

Molecular Formula

C35H33N7O11

Molecular Weight

727.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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