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SJYHJ-026

Product Specifications

Target

PROTACs

Related Pathways

PROTAC

Bioactivity

SJYHJ-026 (compound 37) is a pregnane X receptor (PXR) degrader with a DC50 value of 86.6 nM and a maximum degradation efficacy of 66.4%. This compound demonstrates cytotoxicity in SNU-C4 HiBiT-PXR KI cells, with IC50 values of 97.4 μM (24 h) and 99.5 μM (72 h) .

Smiles

O=C(CC)[O-].O=C(CC)[O-].[Ca+2]

Molecular Formula

C60H84N8O11S

Molecular Weight

1125.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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