4''-C18 EGCG
Product Specifications
Target
Glucosidase
Related Pathways
Metabolism
Bioactivity
4''-C18 EGCG is an effective inhibitor of α-amylase and α-glucosidase, with IC50 values of 3.74 and 0.81 μM, respectively. This compound suppresses carbohydrate-hydrolyzing enzymes, reduces oxidative stress and inflammation, and exhibits anti-diabetic activity. Moreover, 4''-C18 EGCG downregulates pro-inflammatory cytokines and demonstrates cytotoxicity at 50 μM against primary human peripheral blood mononuclear cells (PBMC), as well as non-cancerous cell lines 3T3-L1 and HEK 293.
Smiles
N(C(=O)C=1C=C(ON1)C2=CC(O)=C(C(N(C)C)=O)C=C2)[C@H]3C=4C(CC3)=CC=C(C(O)=O)C4
Molecular Formula
C40H54O11
Molecular Weight
710.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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