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Toladryl

Product Specifications

CAS Number

19804-27-4

Target

Endogenous Metabolite, Histamine Receptor, iGluR

Related Pathways

Membrane transporter/Ion channel, GPCR/G Protein, Immunology/Inflammation, Neuroscience, Metabolism

Bioactivity

Toladryl is a derivative of Diphenhydramine that can cross the blood-brain barrier and exhibits oral activity, with antihistamine and anticholinergic properties. Its anticholinergic effects are approximately a tenth of those seen with Diphenhydramine, yet it offers 2-4 times the protection against lethal doses of histamine in guinea pigs. The side effects of Toladryl are fewer and milder compared to Diphenhydramine; however, at higher doses, it may cause symptoms such as insomnia, agitation, and disorientation related to the central nervous system. Toladryl is utilized in the research of allergic diseases.

Smiles

O(CCN(C)C)C(C=1C=CC=CC1)C2=CC=C(C=C2)C

Molecular Formula

C18H23NO

Molecular Weight

269.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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