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PROTAC METTL3 degrader 1

Product Specifications

Target

PROTACs

Related Pathways

PROTAC

Bioactivity

PROTAC METTL3 degrader 1 (Compound KH12) is a VHL-based degrader of METTL3, demonstrating a DC50 of 220 nM in MOLM-13 cells. This compound inhibits the METTL3/14 complex with an IC50 of 341 nM and exhibits antiproliferative activity against AML cells.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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