PROTAC METTL3 degrader 1
Product Specifications
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTAC METTL3 degrader 1 (Compound KH12) is a VHL-based degrader of METTL3, demonstrating a DC50 of 220 nM in MOLM-13 cells. This compound inhibits the METTL3/14 complex with an IC50 of 341 nM and exhibits antiproliferative activity against AML cells.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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