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TH9028

Product Specifications

CAS Number

2379556-15-5

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

TH9028 is an inhibitor of MTHFD2, featuring an IC50 value of 11 nM. It demonstrates specific inhibitory activity with IC50 values of 7.97 nM, 27 nM, and 0.5 nM against hMTHFD2, MTHFD2L, and MTHFD1, respectively.

Smiles

N(C(NC1=C(N)NC(N)=NC1=O)=O)C=2C=CC(C(N[C@@H](CCC=3NN=NN3)C(O)=O)=O)=NC2

Molecular Formula

C16H18N12O5

Molecular Weight

458.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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