TH9028
Product Specifications
CAS Number
2379556-15-5
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
TH9028 is an inhibitor of MTHFD2, featuring an IC50 value of 11 nM. It demonstrates specific inhibitory activity with IC50 values of 7.97 nM, 27 nM, and 0.5 nM against hMTHFD2, MTHFD2L, and MTHFD1, respectively.
Smiles
N(C(NC1=C(N)NC(N)=NC1=O)=O)C=2C=CC(C(N[C@@H](CCC=3NN=NN3)C(O)=O)=O)=NC2
Molecular Formula
C16H18N12O5
Molecular Weight
458.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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