TS-002266
Product Specifications
CAS Number
2702325-64-0
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9818
Bioactivity
TS-0022666 is a selective TUT4/7 inhibitor exhibiting antiproliferative and anti-leukaemic activity in vivo and in vitro. It enhances THP-1 cell sensitivity to BCL-2 inhibition, reduces uridylation, and may be used to study cancers with FOCAD deficiency.
Smiles
O=C1C=2C(N(C=C1C(O)=O)C=3C=CC(=NC3)N4CC(N(C)C)C4)=CC(=C(Cl)C2)N5[C@@H](COC6=C(Cl)C(OC)=CC=N6)CCC5
Molecular Formula
C31H32Cl2N6O5
Molecular Weight
639.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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