PROTAC 20S proteasome subunit β5 degrader 1
Product Specifications
Target
Apoptosis, PROTACs
Related Pathways
Apoptosis, PROTAC
Bioactivity
PROTAC 20S proteasome subunit β5 degrader 1 (compound 12f) serves as a targeted degrader of the 20S proteasome subunit β5, exhibiting a DC50 value of 0.11 μM in FaDu cells. This compound disrupts the cell cycle and promotes apoptosis (apoptosis), while inhibiting cell proliferation and migration in both FaDu and KM3/BTZ cells. It is applicable for research into resistance to Bortezomib in pharyngeal carcinoma and multiple myeloma.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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