BPU17
Product Specifications
CAS Number
2198977-68-1
Target
Others, Mitochondrial Metabolism
Related Pathways
Others, Metabolism
Bioactivity
BPU17 interacts with PHB1 and disrupts the PHB1-PHB2 interaction, causing slight mitochondrial dysfunction. This damage hinders transcription dependent on SRF/CArG-box, thereby inhibiting epithelial-mesenchymal transition (EMT) in retinal pigment epithelial cells (RPEs) . BPU17 has demonstrated anti-fibrotic activity in vivo. It holds potential as a research agent for anti-angiogenic age-related macular degeneration (nAMD) .
Smiles
O=C(NC1=CC=C(Cl)C=C1)NC(=O)C2CCC2
Molecular Formula
C12H13ClN2O2
Molecular Weight
252.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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