What is the catalog number for PARP1/BRD4-IN-3?

The catalog number for PARP1/BRD4-IN-3 is T200653.

What sizes are available for PARP1/BRD4-IN-3?

PARP1/BRD4-IN-3 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PARP1/BRD4-IN-3 come in?

PARP1/BRD4-IN-3 is available in 2 different pack sizes.

Is PARP1/BRD4-IN-3 in stock?

PARP1/BRD4-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PARP1/BRD4-IN-3?

PARP1/BRD4-IN-3 is manufactured by Molfinity.

What is the estimated delivery time for PARP1/BRD4-IN-3?

Estimated delivery time for PARP1/BRD4-IN-3 is approximately 10 business day(s), depending on your location.

PARP1/BRD4-IN-3

Product Specifications

Target

DNA/RNA Synthesis, Apoptosis, Epigenetic Reader Domain, PARP

Related Pathways

Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis

Bioactivity

PARP1/BRD4-IN-3 (compound HF4) is an effective inhibitor of BRD4 and PARP1, with IC50 values of 1210 nM and 2019 nM respectively. The compound exhibits antiproliferative activity, induces apoptosis (apoptosis) and cell cycle arrest at the G0/G1 phase. Additionally, PARP1/BRD4-IN-3 causes DNA damage and reduces the expression of the Rad51 protein, demonstrating anti-tumor activity.