YM-I-26
Product Specifications
CAS Number
2585015-90-1
Target
Interleukin, NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.
Smiles
O=C(N(CC1=CC(Cl)=CC=C1OCCC)CCC2=CC=C(C=C2)S(=O)(=O)N3CCOCC3)CC4=CSC=C4
Molecular Formula
C28H33ClN2O5S2
Molecular Weight
577.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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